
Dr. Lily Houghton enlists the aid of wisecracking skipper Frank Wolff to take her down the Amazon in his dilapidated boat. Together, they search for an ancient tree that holds the power to heal – a discovery that will change the future of medicine.
Top Cast

Dwayne Johnson as Frank Wolff

Emily Blunt as Dr. Lily Houghton

Edgar Ramírez as Lope de Aguirre

Jack Whitehall as McGregor Houghton

Jesse Plemons as Prince Joachim
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