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Karen Best has a big life. She's a big girl with a big personality and a big love of Chardonnay, which occasionally, causes her to make some big mistakes with men. But the biggest thing about Karen is her big heart, a heart she uses to excel at her job as a counselor at a group home for young adults with Down syndrome located in an old brownstone in New York City.
Top Cast
Bridget Everett as Karen Best
Karen Pittman as Raquel
Loni Anderson as Jean
Luke Zimmerman as Andy
Joshua Eber as Jerry
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